for the First time came after the Chinese data, several cloned monkeys with an artificially generated gene defect in the world. To contribute to the exploration of circadian disturbances, such as the official Xinhua news Agency with reference to two articles in the Chinese science magazine “National Science Review,” writes. The five macaques had recently been in the Institute of neuroscience of the Chinese Academy of Sciences, Shanghai born.
research on the cloned monkey, the focus is on the so-called circadian rhythm. He is brought, if he is disturbed, people with sleep disorders, Depression, Diabetes, cancer, and diseases such as Alzheimer’s disease. For the first time were the scientists, so that five monkeys with the same genetic Background, wrote Xinhua.
trade-off between the Benefits and suffering
Eckhard Wolf from the gene centre of the Ludwig-Maximilians-University of Munich, called the research a “huge logistical performance”. If ethical and scientific evidence, so an Experiment is necessary, think it not objectionable. You should but the question is: “What’s the Benefit for the people against the suffering inflicted on the animal,” he said. This is each Time a individual decision.
The publication follows on from the scandal of a Chinese researcher who had announced in November the world’s first birth of genetically engineered babies. A woman is still pregnant. His Experiment has triggered global outrage. The University has separated now from the researchers, Chinese authorities consider criminal action against the man.
“Compliance with Standards for animal research,”
The Chinese state news Agency stressed that the current research programme had been monitored by the ethics Committee of the Institute “in Accordance with international Standards for animal research”. Also, the 2017 for the first time in China, the successful cloning of monkeys is controversial, because the primates are so similar, and that the concern for an application of the method in humans is growing.
In the current Experiment, the researchers have changed according to information from embryos of the macaque that are genetically engineered, so that the fabric BMAL1 has been turned off. This is for the regulation of the circadian rhythm is responsible. The genetically modified monkey, which had the most significant disease characteristics, has been cloned, the researchers report.
the nucleus of the cell had been transferred to a seedless egg. It is the same method, with the help of 2017, the first clone monkeys, Zhong Zhong, and Hua Hua had arisen – some 22 years after the birth of clone sheep Dolly. The Director of the Institute, Muming Poo, said that research with cloned monkeys will focus on various diseases of the Brain. The effectiveness of drugs should be tested.